EZChrom Elite

EZChrom Elite is the complete solution to your Chromatography Data System needs. This premier 32-bit product, suited for both stand-alone and Client/Server environments, is the second generation of the popular EZChrom chromatography data system. Over 45,000 EZChrom systems have been shipped to organizations throughout the world and over 100,000 chromatography channels are currently collecting data using EZChrom. Attention to quality and careful incorporation of customer-requested features drives the development of EZChrom Elite. No wonder it was rated "Overall Best" Chromatography Data System in a recent survey conducted by SDi (Strategic Direction International).

EZChrom Elite provides complete laboratory data acquisition, instrument control, and analysis. Read on to discover what this popular data system can do for your laboratory.

Ease of Use

The Widest Variety of Instrument Control

EZChrom Elite has the most comprehensive offering of instrument control of any data system available, providing Complete control of all your laboratory instruments from a single data system!

• Digital control and acquisition for the Agilent 5890 including the A, the Series II, and Series II Plus. Control of the Agilent 5890 can be via IEEE-488 or RS-232.
• Agilent 6890 and Agilent  6890 Plus and the Agilent 6850.
• A wide variety of Agilent autosamplers, including the 7673, (with or without dual tower) and the 7683.
• Agilent (MTI) micro GC control.
• New Agilent 1100 control including the DAD (Diode Array Detector). DAD package also contains a comprehensive 3D analysis and spectral manipulation package with spectral library support.
• Varian/CP line of micro GC's.
• Varian/CP 3800, and 8200/8400 autosamplers.
• Support of the Shimadzu VP series LC and the GC-17.

Reporting

EZChrom Elite provides a variety of reporting options. Ranging from predefined and packaged reports to fully customized reports, EZChrom Elite alleviates the need to use separate software packages to provide results in the format you want.

• Custom Reports: EZChrom Elite gives full control to the user when it comes to developing a method report. Add chromatograms and reports with a click of the mouse. The chromatogram can be zoomed and re-sized on the report template. Insert logos, chromatogram overlays, text boxes, or even video clips into your custom report. You have complete control over fonts, colors, orientation, and the size of items on your report.
• Advanced Reports: Anyone who has used Microsoft's Excel® will be immediately comfortable with EZChrom Elite's Advanced Reporting feature. Using spreadsheet power to create custom reports brings a new level of control in formatting sequence summary reports and providing results that are meaningful and complete. Complete reporting without the use of extra programs means more efficient data management.

Custom Parameters

Create your own customized calculations that are automatically generated with each analysis. Custom parameters are available for reporting, export, and annotation.

Graphical Integration Events

EZChrom Elite Graphical integration events make getting perfect peak integration easy. Chromatogram overlays and on-screen graphical integration programming provide an innovative, visual approach to data analysis. Manual integration tools like manual baseline provide added flexibility. You can even create specialized one-time integration events that are applied to a single chromatography run. Because all integration events are saved with the original data file, it is easy to re-create the integration, even if the method has changed.

Automation Interface

EZChrom Elite is perfect for laboratories with large volumes of routine analyses; the Automation Interface can simplify operation by customizing the user interface to the laboratory's specification. The Automation Interface Toolkit allows you to write your own custom user interface. This makes using EZChrom Elite as simple as choosing an instrument and a method, entering a sample name, and pressing "Start Run." No other chromatography data system is as flexible as EZChrom Elite.

Advanced System Administration Tools

EZChrom Elite's unique design provides network-wide data management and security. Because each user and group on the system is defined through the Windows NT domain controller, the integrity of network security and its shared resources is maintained. EZChrom Elite makes setup and maintenance of laboratory projects, instruments, and users easy through the use of System Administration Wizards. These Wizards enable the System Administrator to quickly assign user and group access to individual instruments, laboratories, or even entire buildings. Projects setup ensures consistent storage of data and method files. And command-level user access adds an additional level of control and simplicity.

Audit Trails

EZChrom Elite’s Method Audit trail is a permanent part of the method and contains comprehensive information including date of change, user, change (including previous value), and reason for the change. The method audit trail can be viewed on-screen, or printed. Because the original method is saved at the time the data file is acquired, it is always possible to re-create the original results, even if the method has been modified.

EZChrom Elite’s Data Audit trail is a permanent part of the data file and tracks activities using the stored data file. It includes time, user, activity (such as new analysis) and the reason and is stored as part of the data file. The audit trail can be displayed on-screen or printed.

Electronic Signature

EZChrom Elite fully complies with 21 CFR Part 11 Electronic Signature requirements. In addition to the display of electronic signatures on the report, the signature information (Who, When, and Why) is stored within the data file with a CRC checksum to prevent tampering with the signature record. This information is also logged in the data file audit trail.

Acquisition Devices

EZChrom Elite provides data acquisition using a variety of options. The NEW SS420X external A/D with RS-232C and with sampling rates of up to 120 Hz. EZChrom Elite also supports data acquisition using the PE Nelson Series 900 or 760 A/D interfaces. Signals can also be acquired digitally from supported instruments, such as the Agilent 5890 and 6850 gas chromatographs, 1100 liquid chromatographs, and others. Each EZChrom Elite system can support acquisition from a number of different A/D sources simultaneously for maximum efficiency.

For more detailed information about our SS420X, click here.

Optional Programs

EZChrom Elite has a variety of optional packages for specialized applications.

GPC/SEC
The calculations and calibrations for SEC are significantly different from traditional chromatography. The EZChrom Elite GPC/SEC Software option supports Narrow Standards, Broad Standards, and Universal calibration techniques. Results can be reported in a variety of ways, including:

• Summary Report: Includes molecular weight distribution calculated values (Weight Average, Number Average, Z Average, Z+1 Average, Viscosity Average molecular weights and Polydispersity index).
• Slice Report: Includes elution time/volume, area, molecular weight, % area and cumulative area for each time slice.
• Chromatograms: Print with annotation for the points of the various molecular weight average results (M_w, M_n, M_z, etc.) and integral line for the cumulative area percent.
• Calibration Curve Display: Print with log molecular weight vs. time or volume, r² values showing goodness of fit to the curve, and calibration points that you can graphically select or deselect.

System Suitability
EZChrom Elite's System Suitability option integrates directly into the chromatography software, enabling you to set up customized system suitability calculations and reports along with your method for maximum efficiency and ease: Narrow Standards, Broad Standards, and Universal.

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Data Acquisition

The EZChrom Elite^TM chromatography data system provides data acquisition using a variety of options. The NEW SS420X external A/D with RS-232C and with sampling rates of up to 120 Hz. EZChrom Elite also supports data acquisition using the PE Nelson Series 900 or 760 A/D interfaces. Signals can also be acquired digitally from supported instruments, such as the Agilent 5890 and 6850 gas chromatographs, 1100 liquid chromatographs, and others. Each EZChrom Elite system can support acquisition from a number of different A/D sources simultaneously for maximum efficiency.

For more detailed information about our SS420X, see below.

SS420x High Resolution Chromatography A/D Module

The SS420x is an intelligent analog to digital conversion module that provides remote acquisition for up to 4 channels of data. With 1 MB of memory, the SS420x continues to acquire data regardless of the state of the controlling computer.

Continuing Performance

The SS420x inherits the legacy of the original SS420 Instrument Interface. Over the years, thousands of SS420s have impressed users with their low noise, high linearity, and reliability.

The SS420x supports asynchronous acquisition from four channels, has four built in triggers, and eight relays for programmable switching applications. It shares the same proven 24-bit analog data acquisition that has established Scientific Software, Inc. as a leader in analog acquisition. A rigorous factory calibration and testing program ensures trouble free operation.

Serial Communication

The SS420x connects to the PC via RS232 communication. A valuable feature of the RS232 is that the SS420x can be over 100 feet away from the computer. Now acquisition can occur from tight spaces, remote locations, or other areas where a PC may not be permitted.

Network Friendly

Some A/D converters interface directly to the network. A continuous stream of digital signal is transmitted on the network, and if there is any interruption in transmission, precious data may be corrupted or lost.

The SS420x acquisition occurs between the instrument and the PC, with no access required to the network. This not only reduces network load, but also enables data acquisition to continue even if the network goes down.

Intelligent Redundancy

Each SS420x has its own power supply, so in the event that the PC should lose power, acquisition will continue. It retains over an hour of data for each channel, depending upon acquisition speed.

A built-in CPU manages information flow from the SS420x to the computer, ensuring that information transmitted safely from the module to the computer.

System Status is Easy to Observe

LED status indicators, which provide start-up, data acquisition, reprogramming, and error status are positioned to allow quick observation of system activity.

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System Validation

SS120C Chromatogram Generator (pdf data sheet 142kb)
The SS120C is a 21-bit, Ultra High Resolution Signal Generator that can assist you in validating your chromatography data handling software and A/D hardware. The SS120C stores digital representations of the chromatographic patterns and outputs the patterns as an analog (voltage) signal, just like your chromatography system detector. Because the digital values do not change and the digital to analog converter is highly accurate, the same signal is output every time. The SS120C is factory calibrated using NIST traceable instrumentation, so its accuracy is guaranteed. The SS120C is portable, using battery or line power, for optimum noise immunity. The rechargeable battery is capable of four hours of continuous operation between charges.

The SS120C has four built-in patterns to test the accuracy and reproducibility of your data system. These patterns can be generated in either 1 V full scale or 10 V full scale ranges:

Gaussian full scale peaks: Tests the reproducibility of data system integration.

Gaussian/2: Tests the linearity of data system peak measurement. The first peak in a series is full scale. Each successive peak is one-half the size of the previous peak.

Stair Case, full scale: Tests the accuracy of the data system A/D converter over its full scale range. The output voltage is changed in precise increments over the selected full range scale.

Stair Case, 100mV:  Tests the accuracy of the data system A/D converter over the lower part of its range. The output voltage is changed in precise increments over a 100mV range.

Virtual Peak Generator Program
Create any chromatogram you wish! Build a trace that relates to your analysis and download it directly to the SS120C! Then, accurately replay any instrument time and time again. You can test your integrator to the fullest by adding noise, bunch peaks and  a drift. This program is remarkably easy to use. With just a few clicks, you'll be stretching your data system to the limit.

Chromatogram Testing Package
Chromatograms are available to test multi-level calibrations and a wide variety of peak integration parameters. The chromatograms are in standard ANDI *.CDF format (specified by the Analytical Instrument Association & supported by the major data system suppliers). In addition, these chromatogram files can be downloaded to the SS120C Chromatogram Generator for replay to your data system, using the Virtual Peak Generator software.

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